Does ketotifen have a steroid-sparing effect in childhood asthma?
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منابع مشابه
Does ketotifen have a steroid-sparing effect in childhood asthma?
In view of the possible systemic side-effects of inhaled corticosteroids (ICS), a study was performed to determine whether ketotifen (versus placebo) can replace or allow a reduction in the dose of ICS required for the maintenance treatment of childhood asthma. Sixty six children (aged 6-13 yrs) with asthma (confirmed by methacholine challenge), who were maintained on ICS, at a dose of < or = 1...
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A randomised, double blind, placebo controlled trial of nedocromil sodium was undertaken to assess its corticosteroid sparing effect in 50 adults with asthma who had required an oral corticosteroid dose of (or equivalent to) at least 5 mg prednisolone a day continuously during the preceding year, in addition to inhaled beclomethasone dipropionate and bronchodilators. Patients having corticoster...
متن کاملKetotifen in the prophylaxis of childhood asthma.
nor unique. Every acute children's ward has its problems which are the outcome of its history and geography; all share the problem of being at the mercy of unpredictable factors and of emergency admissions. They suffer also from the problem of having to have 3 different sizes of bed or cot. I am certain that similar experiences are common in district general hospitals throughout the country. Th...
متن کاملKetotifen in adult asthma.
The efficacy and adverse effects of ketotifen 1 mg twice daily and 2 mg twice daily were compared with placebo in 50 patients with atopic asthma in a multicentre, double-blind study. Ketotifen in the higher dosage caused a slight reduction in salbutamol usage and a modest improvement in breathing in patients not already receiving inhaled corticosteroids. The drug was ineffective in patients rec...
متن کاملKetotifen versus inhaled budesonide for controlling childhood asthma.
BACKGROUND International asthma guideline recommends inhaled corticosteroids therapy for children of all ages as the first controller. However, in some less developed parts of the world, ketotifen, an old inexpensive medicine with antihistaminic and anti-allergic reactions, has been found to be the most favored prophylactic agents. OBJECTIVE To compare the efficacy and safety of ketotifen and...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 1997
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.97.10010065